Direct interaction of endothelial nitric-oxide synthase and caveolin-1 inhibits synthase activity
Multiple-dose vials should never be shared between patients, and each withdrawal should be performed with a new, sterile needle and syringe
Eslam, M., Valenti, L
This could explain why tirzepatide (which stimulates the GIP pathway in addition to GLP -1) can be administered at higher doses than semaglutide (which only stimulates GLP-1), without amplifying the side effects typical of GLP-1 agonists (nausea, vomiting)
Meanwhile, you can barely drag yourself out of bed, your libido is non-existent, and you're wondering if this is just what getting older feels like
Author contributions AM: Writing original draft, Investigation, Conceptualization, Writing review & editing, Data curation, Formal Analysis, Methodology